DESPONDENCE Scrabble 17 Words With Friends 21 Scrabble letter values: D2E1S1P3O1N1D2E1N1C3E1 = 17 Definition noun feeling downcast and disheartened and hopeless. — synonyms: despondency, heartsickness, disconsolateness See all 236 words you can make from DESPONDENCE → 11-letter words Words starting with D Words ending with E ← Unscramble different letters