DOOFUS /ˈduːfəs/ ► audio Scrabble 10 Words With Friends 11 Definition noun a stupid incompetent person. — synonyms: dimwit, nitwit, half-wit Examples “Danny is such a doofus!” See all 22 words you can make from DOOFUS → 6-letter words Words starting with D Words ending with S ← Unscramble different letters