INEFFICACY Scrabble 23 Words With Friends 25 Scrabble letter values: I1N1E1F4F4I1C3A1C3Y4 = 23 Definition noun a lack of efficacy. — synonyms: inefficaciousness See all 74 words you can make from INEFFICACY → 10-letter words Words starting with I Words ending with Y ← Unscramble different letters