INSANE /ɪnˈseɪn/ Scrabble 6 Words With Friends 8 Definition adjective afflicted with or characteristic of mental derangement. adjective very foolish. — synonyms: harebrained, mad Examples “an insane asylum”“an insane amount of money” Anagrams of INSANE inanessienna See all 41 words you can make from INSANE → 6-letter words Words starting with I Words ending with E ← Unscramble different letters