KEYNOTE /ˈkiːˌnoʊt/ Scrabble 14 Words With Friends 14 Definition verb set the keynote of. verb give the keynote address to (an audience). noun the principal theme in a speech or literary work. noun a fundamental or central idea. noun (music) the first note of a diatonic scale. — synonyms: tonic See all 55 words you can make from KEYNOTE → 7-letter words Words starting with K Words ending with E ← Unscramble different letters