MANACLE /ˈmænək(ə)l/ ► audio Scrabble 11 Words With Friends 15 Definition verb confine or restrain with or as if with manacles or handcuffs. — synonyms: cuff, handcuff noun shackle that consists of a metal loop that can be locked around the wrist. — synonyms: handcuff, cuff, handlock See all 71 words you can make from MANACLE → 7-letter words Words starting with M Words ending with E ← Unscramble different letters