adjective very irritable.
— synonyms: bristly, splenetic, waspish
adjective having or covered with protective barbs or quills or spines or thorns or setae etc..
— synonyms: barbed, barbellate, briary, briery, bristled, bristly, burred, burry
Examples
“The prickly pear is a cactus; you have to peel it before eating it to remove the spines and the tough skin.”
“He has a prickly personality. He doesn't get along with people because he is easily set off.”