PUFFIEST Scrabble 16 Words With Friends 18 Definition PUFFIEST is the superlative of PUFFY. adjective PUFFY: being puffed out. Examples “A puffy fat man in a tracksuit came jogging around the corner.” See all 103 words you can make from PUFFIEST → 8-letter words Words starting with P Words ending with T ← Unscramble different letters