TUPELO Scrabble 8 Words With Friends 11 Definition noun pale soft wood of a tupelo tree especially the water gum. noun any of several gum trees of swampy areas of North America. — synonyms: tupelo_tree noun a town in northeast Mississippi. See all 46 words you can make from TUPELO → 6-letter words Words starting with T Words ending with O ← Unscramble different letters