UPTOWN Scrabble 11 Words With Friends 14 Definition adverb toward or in the upper part of town. adjective of or located in the upper part of a town. noun a residential part of town away from the central commercial district. Examples “Let's go uptown and try out that new restaurant.” See all 40 words you can make from UPTOWN → 6-letter words Words starting with U Words ending with N ← Unscramble different letters