VERTEBRATE /ˈvɛɹ.tɪ.bɹeɪt/ Scrabble 15 Words With Friends 17 Definition adjective having a backbone or spinal column. noun animals having a bony or cartilaginous skeleton with a segmented spinal column and a large brain enclosed in a skull or cranium. — synonyms: craniate See all 136 words you can make from VERTEBRATE → 10-letter words Words starting with V Words ending with E ← Unscramble different letters