MANACLES /ˈmæn.ə.kəlz/ Scrabble 12 Words With Friends 16 Definition MANACLES is the plural of MANACLE. verb MANACLE: confine or restrain with or as if with manacles or handcuffs. See all 167 words you can make from MANACLES → 8-letter words Words starting with M Words ending with S ← Unscramble different letters